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CANCER OF UNKNOWN PRIMARY FOUNDATION

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07 Dec 2024 11 Sep 2024

ESMO have included CUP in their programme and the speakers are our well known CUP researchers: Linda Mileshkin, Alwin Kramer, Natalie Cook, Harpreet Wasan, and Manel Esteller. For the CUP events go to the programme and look at the Toledo venue starting Saturday 14 Sep.

26 Jun 2024

The American Society of Clinical Oncology (ASCO) held its annual meeting in Chicago in June 2024. Although there was limited CUP research presented we wanted to highlight two studies presented as posters at this meeting: The UK CUPCOMP study was presented by Dr Alicia-Marie Conway, University of Manchester, Cancer Research UK National Biomarker Centre and The Christie NHS TRust (photoRead more

24 Apr 2024

Very comprehensible article on how examining circulating tumour DNA from liquid biopsies will change the search for CUP based on the proof of concept research by Dr Conway at The Christie. A new blood test for cancer of unknown primary (cancerresearchuk.org)

23 Apr 2024 20 Feb 2024

Dr Natalie Cook has been awarded a 5-year National Institute for Health and Care Research (NIHR) Rosetrees Trust Advanced Fellowship. The £730,000 award will fund an ambitious and exciting programme of research into cancer of unknown primary (CUP). https://www.christie.nhs.uk/research-and-innovation/research-newsroom/research-news/christie-consultant-awarded-5-year-advanced-clinical-fellowship  

28 Oct 2023

The abstract presented at ESMO by Dr Harpreet Wasan – PI of the CUP-One trial: A prospective double-blind validation of molecular classifiers in the diagnosis of Cancer of Unknown Primary and clinical outcome. CUP-ONE esmo abs

18 Oct 2023

LBA16 – Primary analysis of efficacy and safety in the CUPISCO trial: A randomised, global study of targeted therapy or cancer immunotherapy guided by comprehensive genomic profiling (CGP) vs platinum-based chemotherapy (CTX) in newly diagnosed, unfavourable cancer of unknown primary (CUP) Background With platinum-based CTX, prognosis of patients (pts) with unfavourable CUP is poor; however, CGP may inform treatment strategiesRead more

15 Sep 2023 13 Sep 2023

The DRAFT NICE quality standard on suspected cancer update can be seen here for stakeholder comments by 18 Sep: https://www.nice.org.uk/guidance/indevelopment/gid-qs10176/consultation/html-content-7  The issue for CUP patients has always been around initial presentation (to GPs) with non site-specific symptoms and it is encouraging to see the espoused theory in the update: ‘If results of tests in primary care cannot establish the mostRead more